Basic and Clinical Pharmacology 10e

International Edition - lower price

The current science of pharmacology-and its clinical applications-at your fingertips
Now in its 25th year of publication, Basic and Clinical Pharmacology is the most up-to-date and complete pharmacology textbook available. Through nine previous editions it has set the standard for concise and easy-to-read, yet comprehensive coverage of pharmacology. The texts integration of basic with clinical science makes it well suited for an integrated organ-system-based curricula as well as the more traditional curricula.
Features
- In-depth coverage of key pharmacology topics, from basic principles to pharmacologic considerations for autonomic, cardiovascular-renal, smooth muscle, CNS, endocrine, antimicrobial, and chemotherapeutic and immunotherapeutic drugs
- Updated with dozens of new, recently approved drugs, including monoclonal antibodies
- Detailed review of the mechanism of action and toxicities of traditional and newer drugs
- Critical discussions of treatment strategies and recommended drugs for all major diseases
- Valuable section on toxicology that provides an introduction to occupational and environmental toxicology; heavy metal intoxication and chelators; and management of the poisoned patient
- Ready-to-use, study-enhancing features, including special interest boxes, lists of common preparations, and dosage information
- Unique evidence-based chapters on abused drugs; special aspects of perinatal, pediatric, and geriatric pharmacology; and over-the-counter drugs, herbal medications, and nutritional supplements
- More than 500 concept-clarifying illustrations and tables throughout

• I. BASIC PRINCIPLES
  1. Introduction
  2. Drug Receptors & Pharmacodynamics
  3. Pharmacokinetics & Pharmacodynamics:: Rational Dosing & the Tiem Course of Drug Action
  4. Drug Biotransformation
  5. Basic & Clinical Evaluation of New Drugs
• II. AUTONOMIC DRUGS
  6. Introduction to Autonomic Pharmacology
  7. Cholinoceptor-Activating & Cholinesterase-Inhibiting Drugs
  8. Cholinoceptor-Blocking Drugs
  9. Adrenoceptor-Activating & Other Sympathomimetic Drugs
  10. Adrenoceptor Antagonist Drugs
• III. CARDIOVASCULAR-RENAL DRUGS
  11. Antihypertensive Agents
  12. Vasodilators & the Treatment of Angina Pectoris
  13. Drugs Used in Heart Failure
  14. Agents Used in Cardiac Arrhythmias
  15. Diuretic Agents
• IV. DRUGS WITH IMPORTANT ACTIONS ON SMOOTH MUSCLE
  16. Histamine, Serotonin, & the Ergot Alkaloids
  17. Vasoactive Peptides
  18. The Eicosanoids:: Prostaglandins, Thromboxanes, Leukotrienes, & Related Compounds
  19. Nitric Oxide, Donors, & Inhibitors
  20. Drugs Used in Asthma
• V. DRUGS THAT ACT IN THE CENTRAL NERVOUS SYSTEM
  21. Introduction to the Pharmacology of CNS Drugs
  22. Sedative-Hypnotic Drugs
  23. The Alcohols
  24. Antiseizure Drugs
  25. General Anesthetics
  26. Local Anesthetics
  27. Skeletal Muscle Relaxants
  28. Pharmacologic Management of Parkinsonism & Other Movement Disorders
  29. Antipsychotic Agents & Lithium
  30. Antidepressant Agents
  31. Opioid Analgesics & Antagonists
  32. Drugs of Abuse
• VI. DRUGS USED TO TREAT DISEASES OF THE BLOOD, INFLAMMATION, & GOUT
  33. Agents Used in Anemias; Hematopoietic Growth Factors
  34. Drugs Used in Disorders of Coagulation
  35. Agents Used in Hyperlipidemia
  36. Nonsteroidal Anti-Inflammatory Drugs, Disease-Modifying Antirheumatic Drugs, Nonopioid Analgesics, & Drugs Used in Gout
• VII:: ENDOCRINE DRUGS
  37. Hypothalamic & Pituitary Hormones
  38. Thyroid & Antithyroid Drugs
  39. Adrenocorticosteroids & Adrenocortical Antagonists
  40. The Gonadal Hormones & Inhibitors
  41. Pancreatic Hormones & Antidiabetic Drugs
  42. Agents That Affect Bone Mineral Homeostasis
• VIII:: CHEMOTHERAPEUTIC DRUGS
  43. Beta-Lactam Antibodies & Other Inhibitors of Cell Wall Synthesis
  44. Chloramphenicol. Tetracyclines, Macrolides, Clindamycin, & Streptogramins
  45. Aminoglycosides & Spectinomycin
  46. Sulfonamides, Trimethoprim, & Quinolones
  47. Antimycobacterial Drugs
  48. Antifungal Drugs
  49. Antiviral Agents
  50. Miscellaneous Antimicrobial Drugs:: Disinfectants, Antiseptics, & Sterilants
  51. Clinical Use of Antimicrobial Agents
  52. Basic Principles of Antiparasitic Chemotherapy
  53. Antiprotozoal Drugs
  54. Clinical Pharmacology of the Anthelmintic Drugs
  55. Cancer Chemotherapy
  56. Immunopharmacology
• IX. TOXICOLOGY
  57. Introduction to Toxicology:: Occupational & Environmental
  58. Heavy Metal Intoxication & Chelators
  59. Management of the Poisoned Patient
• X. SPECIAL TOPICS
  60. Special Aspects of Perinatal & Pediatric Pharmacology
  61. Special Aspects of Geriatric Pharmacology
  62. Dermatologic Pharmacology
  63. Drugs Used in Gastrointestinal Diseases
  64. Therapeutic & Toxic Potential of Over-the-Counter Agents, Botanicals, and Nutritional Supplements
  Appendix I. Vaccines, Immune Globulins, & Other Complex
  Biologic Products