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Cardiac Electrophysiology: From Cell to Bedside

9780323447331
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Opis

Rapid advancements in cardiac electrophysiology require todays health care scientists and practitioners to stay up to date with new information both at the bench and at the bedside. The fully revised 7th Edition of Cardiac Electrophysiology:: From Cell to Bedside, by Drs. Douglas Zipes, Jose Jalife, and William Stevenson, provides the comprehensive, multidisciplinary coverage you need, including the underlying basic science and the latest clinical advances in the field.

Szczegóły produktu
Elsevier
59350
9780323447331
9780323447331

Opis

Rok wydania
2017
Numer wydania
7
Oprawa
twarda
Liczba stron
1424
Wymiary (mm)
222 x 281
Waga (g)
2990
  • Section 1 Structural and Molecular Bases of Ion Channel Function

    1. Voltage-Gated Sodium Channels and Electrical Excitability of the Heart

    2. Voltage-Gated Calcium

    3. Voltage-Gated Potassium Channels

    4. Structural and Molecular Bases of Cardiac Inward Rectifier Potassium Channel Function

    5. Mammalian Calcium Pumps in Health and Disease

    6. Structural and Molecular Bases of Sarcoplasmic Reticulum Ion Channel Function

    7. Organellar Ion Channels and Transporters

    8. Molecular Organization, Gating and Function of Connexin-based Gap Junction Channels and Hemichannels

    Section 2 Biophysics of Cardiac Ion Channel Function

    9. Structure-function relations of Heterotrimetric complexes of sodium channel a and ß subunits

    10. Regulation of Cardiac Calcium Channels

    11. Inhibition of Phosphoinositide 3-Kinase and Acquired Long QT Syndrome

    12. Structural Determinants and Biophysical Properties of hERG1 Channel Gating

    13. Molecular Regulation of Cardiac Inward Rectifier Potassium Channels by Pharmacological Agents

    14. Cardiac Stretch-Activated Channels and Mechano-Electric Coupling

    15. Biophysical Properties of Gap Junctions

    16. Excitation-Contraction Coupling

    Section 3 Intermolecular Interactions and Cardiomyocyte Electrical Function

    17. Ion Channel Trafficking in the Heart

    18. Microdomain Interactions of Macromolecular Complexes and Regulation of the Sodium Channel Nav1.5

    19. Fibroblast growth factor homologous factors modulate cardiac calcium channels.

    20. Macromolecular Complexes and Cardiac Potassium Channels

    21. Reciprocity of Cardiac Sodium and Potassium Channels in the Control of Excitability and Arrhythmias

    22. The intercalated disc:: A molecular network that integrates electrical coupling, intercellular adhesion and cell excitability

    23. Function and dysfunction of ion channel membrane trafficking and post translational modification

    24. Feedback Mechanisms for Cardiac-Specific microRNAs and cAMP Signaling in Electrical Remodeling.

    Section 4 Cell Biology of Cardiac Impulse Initiation and Propagation

    25. Stem cell-derived nodal-like cardiomyocytes as a novel pharmacologic tool:: insights from sinoatrial node development and function.

    26. Gene Therapy and Biological Pacing

    27. Intercellular Communication and Impulse Propagation

    28. Mechanisms of normal and dysfunctional Sinoatrial Nodal Excitability and Propagation

    29. Cell Biology of the Specialized Cardiac Conduction System

    30. Cardiac Remodeling and Regeneration

    Section 5 Models of Cardiac Excitation

    31. Ionic Mechanisms of Atrial Action Potentials

    32. Genetic algorithms to generate dynamical complexity electrophysiological models

    33. Calcium Signaling in Cardiomyocyte Models with Realistic Geometries

    34. Theory of Rotors and Arrhythmias

    35. Computational approaches for Accurate Rotor localization in the Human Atria

    36. Modeling the aging heart

    Section 6 Neural Control of Cardiac Electrical Activity

    37. Innervation of the sinoatrial node

    38. Mechanism for altered autonomic and oxidant regulation of cardiac sodium currents.

    39. Pulmonary Vein Ganglia and the Neural Regulation of the Heart Rate

    40. Neural Activity and Atrial Tachyarrhythmias

    41. Sympathetic Innervation and Cardiac Arrhythmias

    Section 7 Arrhythmia Mechanisms

    42. The Molecular Pathophysiology of Atrial Fibrillation

    43. Myofibroblasts, Cytokines, and Persistent Atrial Fibrillation

    44. Role of the Autonomic Nervous System in Atrial Fibrillation

    45. Rotors in Human Atrial Fibrillation

    46. Body surface frequency-phase mapping of atrial fibrillation.

    47. Panoramic Mapping of Atrial Fibrillation from the body surface

    48. Mechanisms of Human Ventricular Tachycardia and Human Ventricular Fibrillation

    49. Genetics of Atrial Fibrillation

    Section 8 Molecular Genetics and Pharmacogenomics

    50. Mechanisms in Heritable Sodium Channel Diseases

    51. Genetic, Ionic and Cellular Mechanisms Underlying the J Wave Syndromes

    52. Inheritable Potassium Channel Diseases

    53. Inheritable Phenotypes Associated With Altered Intracellular Calcium Regulation

    Section 9 Pharmacologic, Genetic and Cell Therapy of Ion Channel Dysfunction

    54. Pharmacologic Bases of Antiarrhythmic Therapy

    55. Pharmacogenomics of Cardiac Arrhythmias

    56. Gene therapy to treat cardiac arrhythmias

    57. Highly Mature Human iPSC-Derived Cardiomyocytes as Models for Cardiac Electrophysiology and Drug Testing

    58. Cardiac repair with human induced pluripotent stem cell-derived cardiovascular cells.

    Section 10 DIAGNOSTIC EVALUATION

    59. Assessment of the patient with a cardiac arrhythmia

    60. Electrocardiography of tachyarrhythmias:: Differential diagnosis of narrow and wide QRS complex tachycardias

    61. Electroanatomic Mapping for arrhythmias

    62. Computed tomography for electrophysiology

    63. Magnetic resonance imaging for electrophysiology

    64. Intracardiac echocardiography for electrophysiology

    65. Exercise-induced arrhythmias

    66. Cardiac monitoring:: short- and long-term recording

    67. Head-up Tilt Table Testing

    68. Autonomic Regulation and Cardiac Risk

    69. T-wave alternans

    70. Noninvasive Electrocardiographic Imaging of Human Ventricular Arrhythmias and Electrophysiological Substrate

    71. Genetic testing

    Section 11 SUPRAVENTRICULAR TACHYARRHYTHIAS:: MECHANISMS, CLINICAL FEATURES, AND MANAGEMENT

    72. Sinus node abnormalities

    73. Atrial tachycardia

    74. Atrial tachycardia in adults with congenital heart disease

    75. Typical and Atypical Atrial Flutter:: Mapping and Ablation

    76. Atrial fibrillation

    77. Preexcitation, Atrioventricular reentry, Variants

    78. Electrophysiological Characteristics of Atrioventricular Nodal Reentrant Tachycardia:: Implications for the Rentrant Circuits

    79. Junctional tachycardia

    Section 12 VENTRICULAR TACHYCARRHYTHMIAS:: MECHANISMS, CLNICAL FEATURES, AND MANAGEMENT

    80. Premature ventricular complexes

    81. Outflow tract ventricular tachycardias:: Mechanisms, Clinical Features, and Management

    82. Fascicular ventricular arrhythmias

    83. Bundle branch reentry tachycardia

    84. Ischemic heart disease

    85. Ventricular Tachycardia in Patients with Dilated Cardiomyopathy

    86. Ventricular Arrhythmias in Hypertrophic Cardiomyopathy

    87. Ventricular Tachycardias in Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy

    88. VTs in Catcholaminergic Cardiomyopathy (Catecholaminergic polymorphic ventricular tachycardia)

    89. Ventricular Arrhythmias in Heart failure

    90. Arrhythmias and conduction disturbances in Non Compaction Cardiomyopathy

    91. Takotsubo cardiomyopathy

    92. Brugada syndrome

    93. Long and short QT syndromes

    94. Anderson-Tawil syndrome

    95. Timothy syndrome

    96. J Wave Syndromes

    97. Idiopathic ventricular fibrillation

    98. Sudden infant death syndrome

    99. Sudden cardiac arrest/death in adults

    100. Neurologic disorders

    101. Drug-Induced Ventricular Tachycardia

    102. Ventricular Arrhythmias in Congenital Heart Disease

    Section 13 SYNCOPE and Bradyarrhythmias

    103. Syncope

    104. Postural orthostatic tachycardia syndrome

    105. Progressive conduction system disease

    106. Atrioventricular block

    Section 14 ARRHYTHMIAS IN SPECIAL POPULATIONS PHARMACOLOGIC THERAPY

    107. Sex differences in arrhythmias

    108. Sudden cardiac death in athletes, inlcuding commotio cordis

    109. Pediatric populations

    110. Sleep-disordered breathing and arrhythmias

    111. Ventricular Assist devices and Cardiac Transplantation Recipients

    Section 15 PHARMACOLOGIC THERAPY

    112. Standard antiarrhythmic drugs

    113. Innovations In Antiarrhythmic Drug Therapy

    114. Nontraditional drugs for sudden cardiac death

    115. Prevention of stroke in atrial fibrillation:: warfarin, anti-factor Xa and thrombin drugs

    Section 16 CARDIAC IMPLANTABLE ELECTRONIC DEVICES

    116. Implantable cardioverter defibrillators:: technical aspects

    117. Implantable cardioverter defibrillators:: clinical aspects

    118. Subcutaneous implantable defibrillator

    119. Implantable pacemakers

    120. Cardiac resynchronization therapy

    121. Newer applications of pacemakers

    122. Remote monitoring

    Section 17 CATHETER ABLATION

    123. Catheter Ablation:: Technical aspects

    124. Catheter Ablation:: Clinical aspects

    125. Ablation for Atrial fibrillation

    126. Ablation of Supraventricular tachycardias

    127. Catheter Abliation for Ventricular tachycardias with/without structural heart disease

    128. Epicardial and other approaches

    129. Ventricular fibrillation

    130. Ablation in Pediatrics

    131. Congenital heart disease

    132. Anesthesiology for EP procedures

    Section 18:: SURGERY FOR ARRHYTHMIAS

    133. Surgery for Atrial fibrillation and other supraventricular tachycardias

    134. Surgery for Ventricular tachycardia

    Section 19 NEW APPROACHES

    135. Cervical vagal stimulation for heart failure

    136. Baroreflex stimulation

    137. Spinal cord stimulation for heart failure and Arrhythmias

    138. Renal artery denervation

    139. Left atrial appendage occlusion/ligation

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