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Drug Information: A Guide for Pharmacists, Sixth Edition

Drug Information: A Guide for Pharmacists, Sixth Edition

9781259837975
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Opis

 The guide pharmacists and students turn to first for cutting-edge coverage of drug information 

The goal of Drug Information:: A Guide for Pharmacists, Sixth Edition is to teach students and practitioners how to effectively research, interpret, evaluate, collate, and disseminate drug information in the most efficient and effective manner possible. Updated to reflect the realities of todays practice, the book also addresses important issues such as the legal and ethical considerations of providing drug information.  

Drug Information:: A Guide for Pharmacists begins by introducing the concept of drug information, including its history, and provides details on the various places drug information specialists may find employment. This is followed by information on how to answer a question, from the process of gathering necessary background information through determining the actual informational need, to answering the question. The chapter on drug information resources includes descriptions of the most commonly used references and  contains new information on apps available to practitioners. As with past editions, practical examples are also provided.

The Sixth Edition has been updated throughout, with chapters from previous editions rearranged to make the subject flow better.  This edition is also enhanced by the addition of new chapters on journal clubs and counterfeit drugs/drug shortages. In addition, coverage of Policy Development, Project Design and Implementation has been greatly expanded. 


Szczegóły produktu
60707
9781259837975
9781259837975

Opis

Rok wydania
2017
Numer wydania
6
Oprawa
miękka foliowana
Waga (g)
1436
  • Chapter One. Introduction to the Concept of Drug Information
    Introduction
    The Beginning
    The Evolution
    Opportunities in Drug Information Specialty Practice
    Summary and Direction for the Future
    Self-Assessment Questions
    Chapter Two. Formulating an Effective Response:: A Structured Approach
    Introduction
    Steps for Answering a Question
    Formulating the Response
    Conclusion
    Self-Assessment Questions
    Chapter Three. Drug Information Resources
    Introduction
    Types of Biomedical Resources
    Tertiary Resources
    Secondary Resources
    Primary Resources
    Alternative Resources
    Conclusion
    Self-Assessment Questions
    Chapter Four. Drug Literature Evaluation I:: Controlled Clinical Trial Evaluation
    Introduction
    Biomedical/Pharmacy Literature
    Approach to Evaluating Research Studies (True Experiments)
    Conclusion
    Self-Assessment Questions
    Chapter Five. Literature Evaluation II:: Beyond the Basics
    Introduction
    Beyond the Basic Controlled Trial
    N-of-1 Trials
    Adaptive Clinical Trials
    Stability Studies/In Vitro Studies
    Bioequivalence Trials
    Programmatic Research
    Observational Study Design
    Reports Without Control Group
    Survey Research
    Postmarketing Surveillance Studies
    Review Articles
    Practice Guidelines
    Health Outcomes Research
    Dietary Supplement Medical Literature
    Getting to a Clinical Decision
    Conclusion
    Self-Assessment Questions
    Abbreviations
    Acknowledgments
    Chapter Six. The Application of Statistical Analysis in the Biomedical Sciences
    Introduction
    Populations and Sampling
    Variables and the Measurement of Data
    Descriptive Statistics
    Common Probability Distributions
    Epidemiological Statistics
    Types of Study Design
    The Design and Analysis of Clinical Trials
    Statistical Inference
    Selecting the Appropriate Statistical Test
    Introduction to Common Statistical Tests
    Conclusion
    Self-Assessment Questions
    Chapter Seven. Pharmacoeconomics
    Introduction
    Pharmacoeconomics:: What Is It and Why Do It?
    Relationships of Pharmacoeconomics to Outcomes Research
    Models of Pharmacoeconomic Analysis
    Assessment of Costs
    Assessment of Outcomes
    Performing an Economic Analysis
    What Is Decision Analysis?
    Steps in Reviewing Published Literature
    Selected Pharmacoeconomic Websites
    Conclusion
    Self-Assessment Questions
    Chapter Eight. Evidence-Based Clinical Practice Guidelines
    Introduction
    Evidence-Based Medicine and Clinical Practice Guidelines
    Guideline Development Methods
    Guideline Evaluation Tools
    Implementation of Clinical Practice Guidelines
    Sources of Clinical Practice Guidelines
    Conclusion
    Self-Assessment Questions
    Chapter Nine. Journal Clubs
    Introduction
    Conducting the Journal Club
    Preparing the Presentation
    Conclusion
    Self-Assessment Questions
    Chapter Ten. Legal Aspects of Drug Information Practice
    Introduction
    Tort Law
    Defenses to Negligence and Malpractice Protection
    Labeling and Advertising
    Direct-to-Consumer (DTC) Drug Information
    Off-Label Use and Informed Consent
    Liability Concerns for Internet/Social Media Information
    Fraud and Abuse
    Intellectual Property Rights
    Privacy
    Industry Support for Educational Activities
    Conclusion
    Self-Assessment Questions
    Chapter Eleven. Ethical Aspects of Drug Information Practice
    Introduction
    Basics of Ethics Analysis
    Resources for Use by Professionals Seeking to Learn More about Medical Ethics, as Applied to Issues Involving Provision of Drug Information
    Structures That Support Ethical Decision Making
    Conclusion
    Self-Assessment Questions
    Chapter Twelve. Professional Communication of Drug Information
    Introduction
    Steps in Writing
    Specific Documents
    Conclusion
    Self-Assessment Questions
    Chapter Thirteen. Pharmacy and Therapeutics Committee
    Introduction
    Organizational Background
    Pharmacy Support of the P&T Committee
    P&T Committee Meeting
    P&T Committee Functions
    Communication Within an Organization
    Conclusion
    Study Questions
    Self-Assessment Questions
    Acknowledgment
    Chapter Fourteen. Drug Evaluation Monographs
    Introduction
    Conclusion
    Self-Assessment Questions
    Acknowledgment
    Chapter Fifteen. Drug Shortages and Counterfeit Drugs
    Introduction
    Drug Shortages
    Counterfeit Drugs
    Conclusion
    Self-Assessment Questions
    Chapter Sixteen. Quality Improvement and the Medication Use System
    Introduction
    The Changing Environment for Health Care Quality
    Purpose of Measuring Quality
    Quality Measures
    Quality Improvement
    Quality in Drug Information
    Publication of Quality Improvement Studies
    Conclusion
    Self-Assessment Questions
    Chapter Seventeen. Medication Misadventures I:: Adverse Drug Reactions
    Introduction
    Impact of Adverse Drug Reactions
    Definitions
    Causality and Probability of Adverse Drug Reactions
    Classification of Adverse Drug Reactions
    Implementing a Program
    The Role of Technology in Adverse Drug Reactions Surveillance
    Reporting Adverse Drug Reactions
    Future Approaches to Pharmacovigilance
    Conclusion
    Self-Assessment Questions
    Chapter Eighteen. Medication Misadventures II:: Medication and Patient Safety
    Introduction
    Definitions:: Medication Errors, Adverse Drug Events, and Adverse Drug Reactions
    The Impact of Errors on Patients and Health Care Systems
    Identification and Reporting of Medication Errors and Adverse Drug Events
    Classification of Error Types
    Classifying Patient Outcomes
    National Reporting
    Managing an Event Reporting System
    Types of Safety Event Analysis
    To Err Is Human
    System Error
    A Just Culture—Not Shame and Blame
    Risk Factors for Errors and Events
    Health Professions Education
    Best Practices for Error Prevention
    Other Principles of Error Management
    Putting It All Together
    Conclusion:: Safety as a Priority
    Self-Assessment Questions
    Chapter Nineteen. Policy, Procedure, and Guideline Development
    Introduction
    Regulatory Considerations
    Practice Document Design and Organization
    Factors Influencing Practice Document Development
    Systematic Method for Practice Document Development and Maintenance
    Conclusion
    Self-Assessment Questions
    Chapter Twenty. Project Management
    Introduction
    Projects, Programs, and Portfolios
    Selecting Projects
    Initiating a Project
    Planning a Project
    Executing a Project
    Monitoring and Controlling a Project
    Closing a Project
    Conclusion
    Self-Assessment Questions
    Chapter Twenty-One. Investigational Drugs
    Introduction
    Definitions
    History of Drug Development Regulation in the United States
    The Drug Approval Process
    The Orphan Drug Act
    Institutional Review Board/Institutional Ethics Committee
    Role of the Health Care Professional
    Conclusion
    Self-Assessment Questions
    Chapter Twenty-Two. Pharmaceutical Industry and Regulatory Affairs
    Introduction
    Opportunities for Health Professionals within Industry
    Regulation of Health Professionals in Industry
    The Code on Interactions with Health Care Professionals
    Fulfillment of MIRs
    AE Reporting
    Staying Connected with Pharmaceutical Industry
    Anatomy of DHHS and FDA
    Division of Drug Information
    Opportunities within the FDA
    Conclusion
    Self-Assessment Questions
    Chapter Twenty-Three. Assessing Drug Promotions
    Introduction
    Ethical Criteria for Medicinal Drug Promotion
    Direct-to-Consumer Advertising (DTCA)
    Promotions to Health Care Professionals
    Conclusion
    Self-Assessment Questions
    Chapter Twenty-Four. Drug Information in Ambulatory Care
    Introduction
    Providing Drug Information in the Ambulatory Care Setting
    Drug Information Responsibilities in Ambulatory Care
    Conclusion
    Self-Assessment Questions
    Chapter Twenty-Five. Drug Information and Contemporary Community Pharmacy Practice
    Introduction
    Pharmacists as Drug Information Providers
    Patient Sources of Drug Information
    A New Model of Drug Information
    Conclusion
    Self-Assessment Questions
    Chapter Twenty-Six. Pharmacy Informatics:: Enabling Safe and Efficacious Medication Use
    Introduction
    Medication Use Process
    Pharmacy Informatics
    Order Entry (Prescribing Stage)
    Order Verification (Transcribing Stage)
    Dispensing
    Administration
    Monitoring
    The Future:: Informatics in the U.S. Health Care System
    Conclusion
    Self-Assessment Questions
    Chapter Twenty-Seven. Drug Information Education and Training
    Introduction
    Drug Information in Pharmacy Curriculum
    Postgraduate Training in Drug Information
    Conclusion
    Self-Assessment Questions
    Appendices
    Appendix 2–1 Example of Drug Information Consult Documentation Form
    Appendix 2–2 Standard Questions for Obtaining Background Information from Requestors
    Appendix 3–1 Performing a PubMed Search
    Appendix 3–2 Selected Primary Literatures Sources
    Appendix 4–1 Drug Literature Assessment Questions for Clinical Trials
    Appendix 5–1 Beyond the Basics:: Questions to Consider for Critique of Primary Literature
    Appendix 8–1 Grade Evidence Profile:: Antibiotics for Children with Acute Otitis Media
    Appendix 11–1 Code of Ethics for Pharmacists
    Appendix 12–1 Question Example
    Appendix 12–2 Abstracts
    Appendix 12–3 Bibliography
    Appendix 13–1 Pharmacy and Therapeutics Committee Procedure
    Appendix 13–2 Formulary Request Form
    Appendix 13–3 P&T Committee Meeting Attributes
    Appendix 13–4 Example P&T Committee Minutes
    Appendix 13–5 Chairperson Skills
    Appendix 13–6 Conflict of Interest Declaration
    Appendix 14–1 Format for Drug Monograph
    Appendix 14–2 Example Drug Monograph
    Appendix 16–1 Tools Used in Quality Assurance
    Appendix 16–2 Example of Criteria and Request for Approval
    Appendix 16–3 Example of MUE Results
    Appendix 16–4 Evaluation Form for Drug Information Response
    Appendix 17–1 Kramer Questionnaire
    Appendix 17–2 Naranjo Algorithm
    Appendix 17–3 Jones Algorithm
    Appendix 17–4 Liverpool ADR Causality Assessment Tool
    Appendix 17–5 MedWatch Form
    Appendix 19–1 Policy Example:: High-Alert Medications
    Appendix 20–1 Example of a Project Charter
    Appendix 20–2 Stakeholder Matrix—IV Compounding Software Project
    Appendix 20–3 Example PESTLE Analysis—IV Compounding Software Project
    Appendix 20–4 Example Work Breakdown Structure (WBS)—IV Compounding Software Project
    Appendix 21–1 Investigational New Drug Application
    Appendix 21–2 Statement of Investigator
    Appendix 21–3 Protocol Medication Economic Analysis
    Appendix 21–4 Investigational Drug Accountability Record
    Appendix 22–1 Response Letter Drug A—Incidence of Yellow Stripes
    Glossary
    Answers for Case Studies
    Answers for Self-Assessment Questions
    Index
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